Comparison of Kato-Katz, Ethyl-Acetate Sedimentation, and Midi Parasep® in the Diagnosis of Hookworm, Ascaris and Trichuris infection in the context of an evaluation of rural sanitation in India

This paper by Funk et al. (2013) published in Acta Tropica, summarises the findings of a study conducted seeking to compare STH diagnosis techniques (the Kato-Katz, conventional ethyl-acetate sedimentation, and Midi Parasep® methods) in the context of the Orissa RCT. It found that the Kato-Katz technique gave the best overall diagnostic performance with the highest results in all measures (prevalence, faecal egg count, sensitivity) followed by the conventional ethyl-acetate and then the Midi Parasep® technique. The Kato-Katz technique showed a significantly higher faecal egg count and sensitivity for both hookworm and Trichuris as compared to the Midi Parasep® technique. The conventional ethyl-acetate technique produced smaller pellets and showed lower pellet mobility as compared to the Midi Parasep®.

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